3-羟甲基-1H-喹啉-2-酮合成路线 （共 7 条）
反应条件
sodium tetrahydroborate in methanol 3 h;
参考文献
Uchida; Tabusa; Komatsu; Morita; Kanbe; Nakagawa
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 9 p. 3775 - 3786
反应条件
potassium carbonate in methanol; water T=20°C; 1 h;
参考文献
Basavaiah, Deevi; Reddy, Ravi Mallikarjuna; Kumaragurubaran, Nagaswamy; Sharada, Duddu S
Tetrahedron, 2002 , vol. 58, # 19 p. 3693 - 3697
反应条件
in tetrahydrofuran; water
反应条件
1: 77 percent / Fe / 0.5 h / 110 °C 2: 85 percent / K2CO3 / methanol; H2O / 1 h / 20 °C View Scheme
参考文献
Tetrahedron, , vol. 58, # 19 p. 3693 - 3697
反应条件
1: 89 percent / Fe / 0.5 h / 110 °C 2: 85 percent / K2CO3 / methanol; H2O / 1 h / 20 °C View Scheme
参考文献
Tetrahedron, , vol. 58, # 19 p. 3693 - 3697
反应条件
hydrogen bromide T=70 - 80°C; 3 h;
参考文献
Uchida; Tabusa; Komatsu; Morita; Kanbe; Nakagawa
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 9 p. 3775 - 3786
参考文献
Otsuka Pharmaceutical Co., Ltd.
Patent: US4578381 A1, 1986 ;
