hydrogenchloride; water in diethyl ether T=20°C; 24 h;

sulfuric acid; water; acetic acid 2 h; Reflux;

1: pyridine / methanol / Reflux 2: AgNO2; dipotassium peroxodisulfate; palladium diacetate / 1,2-dichloro-ethane / 48 h / 130 °C / sealed tube 3: hydrogenchloride; water / diethyl ether / 24 h / 20 °C View Scheme

(i) EtNO2, NaOH, EtOH, (ii) aq. HCl; Multistep reaction;