3’-甲基-[1,1’-联苯]-4-甲酸甲酯合成路线 (共 8 条)
反应条件
1: (4-methoxycarbonylphenyl)-boronic acid With iodine; potassium carbonate in acetonitrile T=80°C; 8 h; Inert atmosphereSchlenk techniqueSealed tube; 2: 3-methyl phenyl boronic acid With palladium diacetate in acetonitrile T=80°C; Suzuki Coupling; 14 h; Inert atmosphereSchlenk techniqueSealed tube;
参考文献
Niu, Liting; Zhang, Hao; Yang, Haijun; Fu, Hua
Synlett, 2014 , vol. 25, # 7 art. no. 691, p. 995 - 1000
反应条件
norborn-2-ene; palladium diacetate; caesium carbonate; triphenylphosphine in ethylene glycol dimethyl ether T=90°C; 6 h; Sealed vial;
参考文献
Martins, Andrew; Candito, David A.; Lautens, Mark
Organic Letters, 2010 , vol. 12, # 22 p. 5186 - 5188
反应条件
bis(1,5-cyclooctadiene)nickel (0); potassium phosphate; tri-cyclo-hexyl-phosphine in tetrahydrofuran T=25°C; 6 h; Inert atmosphere;
参考文献
Leowanawat, Pawaret; Zhang, Na; Resmerita, Ana-Maria; Rosen, Brad M.; Percec, Virgil
Journal of Organic Chemistry, 2011 , vol. 76, # 24 p. 9946 - 9955
反应条件
sulfuric acid 6 h; Heating;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , # 1 p. 35 - 38
参考文献
US6335327 B1, ;
Page column 92 ;
参考文献
US6335327 B1, ;
Page column 92 ;
反应条件
hydrogenchloride Combinatorial reaction / High throughput screening (HTS); Product distribution / selectivity;
参考文献
US2007/43234 A1, ;
Page/Page column 51 ;
反应条件
water in methanol T=30 - 50°C; ΔH(excit), ΔS(excit), log A; Rate constantThermodynamic dataKinetics;
参考文献
Ananthakrishnanadar, Ponnambalanad.; Kannan, Nagarathnam
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1984 , # 1 p. 35 - 38