2-(3-丁烯-1-基)苯甲酸合成路线 （共 8 条）
反应条件
1.1: diethyl cyanophosphonate / dimethylformamide / 0.5 h / 0 °C 1.2: Et3N / dimethylformamide / 2 h / 0 °C 2.1: 41 percent / 1,4,8,11-tetraazacyclotetradecane based Ni(II) complex; tetraethylammonium tosylate / dimethylformamide / 60 °C / Electrolysis View Scheme
参考文献
Ozaki, Shigeko; Adachi, Masashi; Sekiya, Sayaka; Kamikawa, Rie
Journal of Organic Chemistry, 2003 , vol. 68, # 11 p. 4586 - 4589
反应条件
1: ortho-methylbenzoic acid With n-butyllithium in tetrahydrofuran; hexane
T=-78 - -20°C; 1.25 h;
2: allyl bromide in tetrahydrofuran; hexane
T=-78 - 20°C; 1.33333 h;
参考文献
Cheng, Yi An; Chen, Tao; Tan, Chong Kiat; Heng, Jun Jie; Yeung, Ying-Yeung
Journal of the American Chemical Society, 2012 , vol. 134, # 40 p. 16492 - 16495,4
反应条件
potassium hydroxide in methanol
参考文献
Roux; Paugam; Rousseau
Journal of Organic Chemistry, 2001 , vol. 66, # 12 p. 4304 - 4310
反应条件
p-tert-butylbenzoic acid methyl ester; tetra-n-butylammonium tetrafluoroborate in N,N-dimethyl-formamide
T=0°C; Electrolysis;
参考文献
Senboku, Hisanori; Michinishi, Jun-Ya; Hara, Shoji
Synlett, 2011 , # 11 p. 1567 - 1572
反应条件
sodium in ethanol
0.75 h; Heating;
参考文献
Scholz, Dieter
Liebigs Annalen der Chemie, 1984 , # 2 p. 264 - 272
反应条件
1: 46 percent / n-BuLi / diethyl ether
2: 90 percent / KOH / methanol
View Scheme
参考文献
Roux; Paugam; Rousseau
Journal of Organic Chemistry, 2001 , vol. 66, # 12 p. 4304 - 4310
反应条件
1.1: TsOH / methanol
1.2: O3 / CH2Cl2
2.1: 46 percent / n-BuLi / diethyl ether
3.1: 90 percent / KOH / methanol
View Scheme
参考文献
Roux; Paugam; Rousseau
Journal of Organic Chemistry, 2001 , vol. 66, # 12 p. 4304 - 4310
反应条件
1: lithium aluminium tetrahydride / tetrahydrofuran / 0 °C / Inert atmosphere
2: pyridinium chlorochromate / dichloromethane / 3 h / 20 °C
View Scheme
参考文献
Li, Yang; Jardine, Katherine J.; Tan, Runyu; Song, Datong; Dong, Vy M.
Angewandte Chemie - International Edition, 2009 , vol. 48, # 51 p. 9690 - 9692
