2,3-二氯-6-(三氟甲基)吡啶合成路线 （共 3 条）
反应条件
1: With hydrogenchloride; sodium nitrite in water T=0°C; 1 h; 2: With copper(l) chloride in water T=40°C; 0.5 h; 3: With ammonium hydroxide in water pH=9;
参考文献
WO2009/117421 A2, ;
Page/Page column 90 ;
WO 2009/117421 A2
反应条件
anhydrous iron chloride; hydrogen fluoride T=170°C; 34 h; Reagent/catalystTemperature;
参考文献
US2013/261310 A1, ;
Paragraph 0078; 0079 ;
反应条件
copper; propionic acid T=135°C; 22 h; Reagent/catalystTemperature;
参考文献
ROSS, JR., RONALD; RENGA, JAMES; BLAND, DOUGLAS C.; ROTH, GARY A.; FUNG, ALEXANDER P.; DAVIS, CLARK S.
Patent: US2013/261310 A1, 2013 ;
Location in patent: Paragraph 0094; 0095 ;
