7,7-二甲基二十碳二烯酸合成路线 （共 9 条）
反应条件
n-butyllithium in tetrahydrofuran; methanol; tetrahydrofuran-hexamethylphosphorictriamide; hexane
参考文献
Hoffmann-La Roche Inc.
Patent: US4434101 A1, 1984 ;
反应条件
potassium hydroxide in methanol
参考文献
Ackroyd; Manro; Scheinmann; et al.
Tetrahedron Letters, 1983 , vol. 24, # 46 p. 5139 - 5140
反应条件
1: 66 percent / pyridinium chlorochromate
2: 53 percent / potassium t-butoxide
3: Na / liquid ammonia
5: pyridinium chlorochromate
6: 61 percent / Bu-Li / tetrahydrofuran; hexamethylphosphoric acid triamide / -78 °C
7: aq. KOH / methanol
View Scheme
参考文献
Ackroyd; Manro; Scheinmann; et al.
Tetrahedron Letters, 1983 , vol. 24, # 46 p. 5139 - 5140
反应条件
1: 53 percent / potassium t-butoxide
2: Na / liquid ammonia
4: pyridinium chlorochromate
5: 61 percent / Bu-Li / tetrahydrofuran; hexamethylphosphoric acid triamide / -78 °C
6: aq. KOH / methanol
View Scheme
参考文献
Ackroyd; Manro; Scheinmann; et al.
Tetrahedron Letters, 1983 , vol. 24, # 46 p. 5139 - 5140
反应条件
2: pyridinium chlorochromate
3: 61 percent / Bu-Li / tetrahydrofuran; hexamethylphosphoric acid triamide / -78 °C
4: aq. KOH / methanol
View Scheme
参考文献
Ackroyd; Manro; Scheinmann; et al.
Tetrahedron Letters, 1983 , vol. 24, # 46 p. 5139 - 5140
反应条件
1: 61 percent / Bu-Li / tetrahydrofuran; hexamethylphosphoric acid triamide / -78 °C
2: aq. KOH / methanol
View Scheme
参考文献
Ackroyd; Manro; Scheinmann; et al.
Tetrahedron Letters, 1983 , vol. 24, # 46 p. 5139 - 5140
反应条件
1: pyridinium chlorochromate
2: 61 percent / Bu-Li / tetrahydrofuran; hexamethylphosphoric acid triamide / -78 °C
3: aq. KOH / methanol
View Scheme
参考文献
Ackroyd; Manro; Scheinmann; et al.
Tetrahedron Letters, 1983 , vol. 24, # 46 p. 5139 - 5140
反应条件
1: Na / liquid ammonia
3: pyridinium chlorochromate
4: 61 percent / Bu-Li / tetrahydrofuran; hexamethylphosphoric acid triamide / -78 °C
5: aq. KOH / methanol
View Scheme
参考文献
Ackroyd; Manro; Scheinmann; et al.
Tetrahedron Letters, 1983 , vol. 24, # 46 p. 5139 - 5140
反应条件
2: 66 percent / pyridinium chlorochromate
3: 53 percent / potassium t-butoxide
4: Na / liquid ammonia
6: pyridinium chlorochromate
7: 61 percent / Bu-Li / tetrahydrofuran; hexamethylphosphoric acid triamide / -78 °C
8: aq. KOH / methanol
View Scheme
参考文献
Ackroyd; Manro; Scheinmann; et al.
Tetrahedron Letters, 1983 , vol. 24, # 46 p. 5139 - 5140
