N,N-dimethyl-formamide in water 1 h; Heating;

1: 81.7 percent / H2O; acetic acid / 48 h / Ambient temperature 2: 81.8 percent / DMF / H2O / 1 h / Heating View Scheme

1: 94.2 percent / 40percent aq. NaOH / methanol / 0.5 h / Heating 2: 81.7 percent / H2O; acetic acid / 48 h / Ambient temperature 3: 81.8 percent / DMF / H2O / 1 h / Heating View Scheme

sodium hydroxide in methanol 2 h; Heating;