4-氟-[1,1-联苯]-2-甲腈合成路线 （共 8 条）
反应条件
Ph2P(CH2CH2O)22CH3; triethylamine; palladium dichloride in water T=80°C; Suzuki coupling; 2 h; Inert atmosphere;
参考文献
Liu, Ning; Liu, Chun; Jin, Zilin
Journal of Organometallic Chemistry, 2011 , vol. 696, # 13 p. 2641 - 2647
反应条件
palladium diacetate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in toluene T=140°C; 24 h; Sealed tubeInert atmosphere;
参考文献
Zhou, Chao; Liu, Qingjiang; Li, Yaming; Zhang, Rong; Fu, Xinmei; Duan, Chunying
Journal of Organic Chemistry, 2012 , vol. 77, # 22 p. 10468 - 10472
反应条件
K3PO4; Pd(PPh3)2Cl2 in toluene T=100°C; 12 h; Schlenk techniqueInert atmosphere;
参考文献
Organic Letters, , vol. 15, # 11 p. 2742 - 2745
反应条件
in benzene Ambient temperature;
参考文献
Sain, Bir; Sandhu, Jagir S.
Journal of Organic Chemistry, 1990 , vol. 55, # 8 p. 2545 - 2546
反应条件
1: toluene / 2 h / 110 °C 2: Pd(PPh3)2Cl2; K3PO4 / toluene / 12 h / 100 °C / |Schlenk technique; |Inert atmosphere View Scheme
参考文献
Organic Letters, , vol. 15, # 11 p. 2742 - 2745
反应条件
potassium acetate; 18-crown-6 ether 1.5 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 49, # 9 p. 1594 - 1603
反应条件
1: potassium phosphate / toluene; water / 0.5 h / 0 - 20 °C 2: 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl; palladium diacetate / toluene / 24 h / 140 °C / |Sealed tube; |Inert atmosphere View Scheme
参考文献
Journal of Organic Chemistry, , vol. 77, # 22 p. 10468 - 10472
反应条件
dichloro bis(acetonitrile) palladium(II); water; silver trifluoroacetate in N,N-dimethyl acetamide; trifluoroacetic acid T=140°C; Heck Reaction; 72 h; GloveboxInert atmosphere;
参考文献
Wan, Jung-Chih; Huang, Jun-Min; Jhan, Yu-Huei; Hsieh, Jen-Chieh
Organic Letters, 2013 , vol. 15, # 11 p. 2742 - 2745
