(5-甲氧基-2-硝基苯基)乙腈合成路线 （共 14 条）
反应条件
chloro-trimethyl-silane T=45°C; 6 h;
参考文献
Cravotto; Giovenzana; Pilati; Sisti; Palmisano
Journal of Organic Chemistry, 2001 , vol. 66, # 25 p. 8447 - 8453
反应条件
hydrogenchloride; water 3 h; Reflux;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 18, # 4 p. 1482 - 1496
反应条件
1: With palladium diacetate; dimethyl sulfoxide; trifluoroacetic acid T=90°C; 24 h; 2: With iron T=90°C; 2 h;
参考文献
Jadhav, Jagannath; Gaikwad, Vipul; Kurane, Rajanikant; Salunkhe, Rajashri; Rashinkar, Gajanan
Synlett, 2012 , vol. 23, # 17 p. 2511 - 2515,5
Title/Abstract Full Text Show Details
Jadhav, Jagannath; Gaikwad, Vipul; Kurane, Rajanikant; Salunkhe, Rajashri; Rashinkar, Gajanan
Synlett, 2012 , vol. 23, # 17 p. 2511 - 2515
反应条件
hydrogen; acetic acid; 10 palladium on active carbon in ethanol P=2280 Torr; 2 h; Ambient temperature;
参考文献
Makosza, Mieczyslaw; Danikiewicz, Witold; Wojciechowski, Krzysztof
Liebigs Annalen der Chemie, 1988 , p. 203 - 208
反应条件
1: 98 percent / K2CO3, 18-crown-6 / acetonitrile / 12 h / Heating 2: 99 percent / H2 / PtO2 / aq. ethanol; ethyl acetate 3: 70 percent / DIBALH / benzene / 1.5 h / 0 °C View Scheme
参考文献
Makosza, Mieczyslaw; Danikiewicz, Witold; Wojciechowski, Krzysztof
Liebigs Annalen der Chemie, 1988 , p. 203 - 208
反应条件
potassium tert-butylate in N,N-dimethyl-formamide
T=-23°C; 2.5 h;
参考文献
Marino; Hurt
Synthetic Communications, 1994 , vol. 24, # 6 p. 839 - 848
反应条件
sodium hydroxide in dimethyl sulfoxide
1 h; Ambient temperature;
参考文献
Makosza, Mieczyslaw; Winiarski, Jerzy
Journal of Organic Chemistry, 1984 , vol. 49, # 9 p. 1494 - 1499
反应条件
nitric acid; acetic anhydride; acetic acid
T=0°C;
参考文献
Mologni, Luca; Rostagno, Roberta; Brussolo, Stefania; Knowles, Phillip P.; Kjaer, Svend; Murray-Rust, Judith; Rosso, Enrico; Zambon, Alfonso; Scapozza, Leonardo; McDonald, Neil Q.; Lucchini, Vittorio; Gambacorti-Passerini, Carlo
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 4 p. 1482 - 1496
反应条件
1: 92 percent / 80percent sodium hydride / tetrahydrofuran / 3 h / Heating
2: 33.5 g / 80percent sodium hydride / dimethylformamide / 3.5 h / 70 °C
3: 1 N Na2CO3 / 120 h / 40 °C
View Scheme
参考文献
Verboom; Lammerink; Egberink; et al.
Journal of Organic Chemistry, 1985 , vol. 50, # 20 p. 3797 - 3806
反应条件
1: potassium ferricyanide
2: 92 percent / 80percent sodium hydride / tetrahydrofuran / 3 h / Heating
3: 33.5 g / 80percent sodium hydride / dimethylformamide / 3.5 h / 70 °C
4: 1 N Na2CO3 / 120 h / 40 °C
View Scheme
参考文献
Verboom; Lammerink; Egberink; et al.
Journal of Organic Chemistry, 1985 , vol. 50, # 20 p. 3797 - 3806
