2-溴-9-(2-脱氧呋喃戊糖基)-9H-嘌呤-6-胺合成路线 （共 7 条）
反应条件
ammonium hydroxide 0.5 h; Irradiation;
参考文献
Helvetica Chimica Acta, , vol. 74, # 8 p. 1742 - 1748
参考文献
Helvetica Chimica Acta, , vol. 74, # 8 p. 1742 - 1748
反应条件
ammonia in methanol
T=60°C; 32 h;
参考文献
Wright, George E.; Hildebrand, Catherine; Freese, Stephen; Dudycz, Lech W.; Kazimierczuk, Zygmunt
Journal of Organic Chemistry, 1987 , vol. 52, # 20 p. 4617 - 4618
反应条件
1: NH3 / ethanol / 100 °C
2: nucleoside deoxyribosyl transferase
View Scheme
参考文献
Huang; Avery; Blakley; Secrist III; Montgomery
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 800 - 802
反应条件
1: Br2, HBr / methanol
2: NH3 / ethanol / 100 °C
3: nucleoside deoxyribosyl transferase
View Scheme
参考文献
Huang; Avery; Blakley; Secrist III; Montgomery
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 800 - 802
反应条件
1: 1.) sodium hydride / 1.) acetonitrile, RT, 1 h, 2.) acetonitrile, RT, 15 min
2: 94 percent / ammonia / methanol / 32 h / 60 °C
View Scheme
参考文献
Wright, George E.; Hildebrand, Catherine; Freese, Stephen; Dudycz, Lech W.; Kazimierczuk, Zygmunt
Journal of Organic Chemistry, 1987 , vol. 52, # 20 p. 4617 - 4618
反应条件
nucleoside deoxyribosyl transferase;
参考文献
Huang; Avery; Blakley; Secrist III; Montgomery
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 800 - 802
