2-氨基-4-氯苯甲酸合成路线

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参考文献

Zeneca Limited
Patent: US5952333 A1, 1999 ;
US 5952333 A

89-77-02-氨基-4-氯苯甲酸→31374-18-27-氯-4(3H)-喹唑啉酮

参考文献

SHANGHAI ALLIST PHARMACEUTICAL., INC.
Patent: EP1990337 A1, 2008 ;
Location in patent: Page/Page column 11 ;

→31374-18-27-氯-4(3H)-喹唑啉酮

参考文献

WO2012/88712 A1, ;

Page/Page column 16 ;

64392-62-7+89-77-02-氨基-4-氯苯甲酸→31374-18-27-氯-4(3H)-喹唑啉酮

参考文献

Stevenson, Thomas M.; Kazmierczak, Franciszek; Leonard, Nelson J.
Journal of Organic Chemistry, 1986 , vol. 51, # 5 p. 616 - 620

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参考文献

Chao, Qi; Deng, Lynn; Shih, Hsiencheng; Leoni, Lorenzo M.; Genini, Davide; Carson, Dennis A.; Cottam, Howard B.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 19 p. 3860 - 3873

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参考文献

Rotella, David P.; Sun, Zhong; Zhu, Yeheng; Krupinski, John; Pongrac, Ronald; Seliger, Laurie; Normandin, Diane; Macor, John E.
Journal of Medicinal Chemistry, 2000 , vol. 43, # 7 p. 1257 - 1263

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参考文献

Bristol-Myers Squibb Company
Patent: US6087368 A1, 2000 ;
US 6087368 A

32315-10-9三光气+89-77-02-氨基-4-氯苯甲酸→40928-13-04-氯靛红酸酐

参考文献

Carter, Malcolm C.; Alber, Dagmar G.; Baxter, Robert C.; Bithell, Sian K.; Budworth, Jo; Chubb, Ann; Cockerill, G. Stuart; Dowdell, Verity C. L.; Henderson, Elisa A.; Keegan, Sally J.; Kelsey, Richard D.; Lockyer, Michael J.; Stables, Jeremy N.; Wilson, Lara J.; Powell, Kenneth L.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 7 p. 2311 - 2319

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参考文献

Hinschberger, Antoine; Butt, Sabrina; Lelong, Veronique; Boulouard, Michel; Dumuis, Aline; Dauphin, Franccois; Bureau, Ronan; Pfeiffer, Bruno; Renard, Pierre; Rault, Sylvain
Journal of Medicinal Chemistry, 2003 , vol. 46, # 1 p. 138 - 147

89-77-02-氨基-4-氯苯甲酸→38154-43-74,7-二氯-2-甲基喹唑啉

参考文献

Yakhontov, L. N.; Zhikhareva, G. P.; Mastafanova, L. I.; Evstratova, M. I.; Pershin, G. N.; et al.
Pharmaceutical Chemistry Journal, 1987 , vol. 21, # 1 p. 34 - 45
Khimiko-Farmatsevticheskii Zhurnal, 1987 , vol. 21, # 1 p. 38 - 49