美沙啦嗪(5-氨基水杨酸)合成路线 （共 91 条）
参考文献
Weil; Traun; Marcel
Chemische Berichte, 1922 , vol. 55, p. 2664
反应条件
man reduziert das Produkt;
参考文献
Bayer and Co.
Patent: DE268791 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 11, p. 396
参考文献
Hirve
Journal of the Indian Chemical Society, 1930 , vol. 7, p. 894
Chem. Zentralbl., 1931 , vol. 102, # I p. 1911
参考文献
Hirve
Journal of the Indian Chemical Society, 1930 , vol. 7, p. 894
Chem. Zentralbl., 1931 , vol. 102, # I p. 1911
反应条件
sulfuric acid in methanol
参考文献
American Cyanamid Company
Patent: US4123455 A1, 1978 ;
参考文献
Knoll Aktiengesellschaft
Patent: US5780482 A1, 1998 ;
反应条件
1.1: 79 percent / H2O / 0.25 h / 50 °C
2.1: 1-hydroxybenzotriazole; N,N'-dicyclohexylcarbodiimide / dimethylformamide / 0.5 h / 0 °C
2.2: 86 percent / dimethylformamide / 0 - 20 °C
3.1: 80 percent / NaOiPr / propan-2-ol / Heating
View Scheme
参考文献
Caliendo, Giuseppe; Santagada, Vincenzo; Perissutti, Elisa; Severino, Beatrice; Fiorino, Ferdinando; Warner, Timothy D; Wallace, John L; Ifa, Demian Rocha; Antunes, Edson; Cirino, Giuseppe; De Nucci, Gilberto
European Journal of Medicinal Chemistry, 2001 , vol. 36, # 6 p. 517 - 530
参考文献
DAK-Laboratoriet
Patent: US4933330 A1, 1990 ;
参考文献
Puxeddu
Gazzetta Chimica Italiana, 1929 , vol. 59, p. 14
参考文献
Puxeddu
Gazzetta Chimica Italiana, 1929 , vol. 59, p. 14
