1-Boc-(3-羧基甲氧基)氮杂丁烷合成路线 （共 2 条）
反应条件
1: 3-hydroxyazetidine-1-carboxylic acid tert-butyl ester With sodium hydride in N,N-dimethyl-formamide T=0°C; 0.25 h; 2: 2-iodoacetic acid sodium salt in N,N-dimethyl-formamide T=20°C; 65 h; 3: With hydrogenchloride in water pH=2;
参考文献
WO2006/67532 A1, ;
Page/Page column 25 ;
WO 2006/067532 A1
反应条件
1: sodium hydride / N,N-dimethyl-formamide / 20 °C 2: palladium; hydrogen / methanol / 20 °C View Scheme
