(R)-1-(乙氧羰基)-3-苯基丙基三氟甲磺酸酯合成路线 （共 10 条）
反应条件
pyridine in dichloromethane T=0°C; 0.5 h;
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 11 p. 1984 - 1991
反应条件
1: 100 percent / p-toluenesulfonic acid*H2O / benzene / 5 h / Heating 2: 29 percent / H2 / 5percent Pd/C / propan-2-ol / 5 h / 50 °C / 2280 Torr 3: 86 percent / KOH / ethanol / 16 h / Ambient temperature 4: 98 percent / conc. H2SO4 / 16 h / Ambient temperature 5: 100 percent / pyridine / CH2Cl2 / 0.5 h / 0 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 11 p. 1984 - 1991
反应条件
1: 29 percent / H2 / 5percent Pd/C / propan-2-ol / 5 h / 50 °C / 2280 Torr 2: 86 percent / KOH / ethanol / 16 h / Ambient temperature 3: 98 percent / conc. H2SO4 / 16 h / Ambient temperature 4: 100 percent / pyridine / CH2Cl2 / 0.5 h / 0 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 11 p. 1984 - 1991
反应条件
1: 98 percent / conc. H2SO4 / 16 h / Ambient temperature 2: 100 percent / pyridine / CH2Cl2 / 0.5 h / 0 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 11 p. 1984 - 1991
反应条件
1: 86 percent / KOH / ethanol / 16 h / Ambient temperature 2: 98 percent / conc. H2SO4 / 16 h / Ambient temperature 3: 100 percent / pyridine / CH2Cl2 / 0.5 h / 0 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 11 p. 1984 - 1991
反应条件
1: N(C2H5)3 / CH2Cl2 / Ambient temperature 2: H2 / Pd/C / ethanol / 760 Torr / Ambient temperature View Scheme
参考文献
Urbach, H.; Henning, R.
Tetrahedron Letters, 1984 , vol. 25, # 11 p. 1143 - 1146
反应条件
1: 10percent aq. Na2CO3 / CH2Cl2 / 5 h / Ambient temperature 2: 91 percent / HCl / CH2Cl2 / 16 h / Ambient temperature View Scheme
参考文献
Attwood, Michael R.; Hassall, Cedric H.; Kroehn, Antonin; Lawton, Geoffrey; Redshaw, Sally
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1986 , p. 1011 - 1020
反应条件
1: 80 percent / Et3N / CH2Cl2 / 16 h / Ambient temperature 2: 94 percent / NaH / dimethylformamide / 5 h / Ambient temperature 3: 78 percent / 4 N aq. HCl / dioxane / 16 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 11 p. 1984 - 1991
反应条件
triethylamine in dichloromethane 16 h; Ambient temperature;
参考文献
Yanagisawa, Hiroaki; Ishihara, Sadao; Ando, Akiko; Kanazaki, Takuro; Miyamoto, Shuichi; et al.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 11 p. 1984 - 1991
反应条件
1: 80 percent / Et3N / CH2Cl2 / 16 h / Ambient temperature 2: 94 percent / NaH / dimethylformamide / 5 h / Ambient temperature 3: 78 percent / 4 N aq. HCl / dioxane / 16 h / Ambient temperature 4: 96 percent / 1 N aq. NaOH / 16 h / Ambient temperature View Scheme
参考文献
Yanagisawa, Hiroaki; Ishihara, Sadao; Ando, Akiko; Kanazaki, Takuro; Miyamoto, Shuichi; et al.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 11 p. 1984 - 1991
