O,O'-双(2,2,2-三氟乙基)磷乙酸甲酯合成路线 （共 27 条）
反应条件
tri[2-(2-methoxyethoxy)ethyl]amine; potassium hexamethylsilazane in tetrahydrofuran; toluene T=-78°C; Horner-Wadsworth-Emmons reaction; 4 h;
参考文献
Touchard, Francois P.
Tetrahedron Letters, 2004 , vol. 45, # 28 p. 5519 - 5523
反应条件
18-crown-6 ether; potassium carbonate in chlorobenzene T=0°C; Horner-Wadsworth-Emmons reaction;
参考文献
Touchard, Francois P.
Tetrahedron Letters, 2004 , vol. 45, # 28 p. 5519 - 5523
反应条件
triethylamine T=20°C; 0.5 h;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 53, # 1 p. 131 - 134
反应条件
18-crown-6 ether; potassium hexamethylsilazane in tetrahydrofuran T=-78°C; Inert atmosphere;
参考文献
Chemistry - A European Journal, , vol. 15, # 35 p. 8722 - 8741
反应条件
18-crown-6 ether; KN(Me4Si)2 in tetrahydrofuran
参考文献
Bartlett; Ting
Journal of Organic Chemistry, 1986 , vol. 51, # 12 p. 2230 - 2240
反应条件
potassium hydride in tetrahydrofuran T=-78°C; 1 h;
参考文献
Annunziata, Rita; Cinquini, Mauro; Cozzi, Franco; Dondio, Gulio; Raimondi, Laura
Tetrahedron, 1987 , vol. 43, # 10 p. 2369 - 2380
反应条件
1: With sodium hydride in ethylene glycol dimethyl ether T=20°C; 1 h; 2: With bromine in ethylene glycol dimethyl ether T=0 - 20°C; 2.25 h;
参考文献
Olpp, Thomas; Brueckner, Reinhard
Synthesis, 2004 , # 13 p. 2135 - 2152
反应条件
18-crown-6 ether; potassium hexamethylsilazane in tetrahydrofuran T=-78°C; Inert atmosphere;
参考文献
Fischer, Daniel F.; Barakat, Assem; Xin, Zhuo-Qun; Weiss, Matthias E.; Peters, Rene
Chemistry - A European Journal, 2009 , vol. 15, # 35 p. 8722 - 8741
反应条件
potassium hexamethylsilazane in tetrahydrofuran; toluene T=-78°C; 0.5 h;
参考文献
Marinier, Anne; Baettig, Kurt; Dallaire, Carol; Pitteloud, Rita; Deslongchamps, Pierre
Canadian Journal of Chemistry, 1989 , vol. 67, p. 1609 - 1617
反应条件
tri[2-(2-methoxyethoxy)ethyl]amine; potassium hexamethylsilazane in tetrahydrofuran; toluene
T=-78°C; Horner-Wadsworth-Emmons reaction; 4 h;
参考文献
Touchard, Francois P.
Tetrahedron Letters, 2004 , vol. 45, # 28 p. 5519 - 5523
