(4-(2-羟基丙烷-2-基)苯基)硼酸合成路线 （共 2 条）
反应条件
1: 4-bromo-α,α-dimethylbenzenemethanol With n-butyllithium in tetrahydrofuran; hexanes
T=-78°C; 3.5 h;
2: tri-isopropoxy-borane in tetrahydrofuran; hexanes
T=20°C; 72 h;
参考文献
PFIZER PRODUCTS INC.
Patent: WO2006/48727 A1, 2006 ;
Location in patent: Page/Page column 75-76 ;
WO 2006/048727 A1
反应条件
1: in diethyl ether
T=20°C; 0.5 h;
2: With hydrogenchloride in diethyl ether; water
参考文献
MERCK FROSST CANADA LTD.
Patent: WO2009/70873 A1, 2009 ;
Location in patent: Page/Page column 70-71 ;
WO 2009/070873 A1
