N-(3-氨基-3-氧代丙基)氨基甲酸苯甲酯合成路线 （共 9 条）
反应条件
hydrogen; palladium on activated charcoal in tetrahydrofuran; methanol 1 h;
参考文献
Seebach, Dieter; Boog, Alois; Schweizer, W. Bernd
European Journal of Organic Chemistry, 1999 , # 1 p. 335 - 360
反应条件
pyridine; trichlorophosphate
参考文献
Grzonka,Z.; Liberek,B.
Roczniki Chemii, 1971 , vol. 45, p. 967 - 980
反应条件
pyridine; bis-(trifluoroacetoxy)-iodo-benzene in water; acetonitrile Ambient temperature;
参考文献
Eisenbrand; Lauck-Birkel; Tang
Synthesis, 1996 , # 10 p. 1246 - 1258
反应条件
1: pyridine; [bis(trifluoroacetoxy)iodo]benzene / dimethylformamide; H2O / 3 h / 0 - 20 °C 2: 304 mg / NaHCO3 / dioxane; H2O / 0 - 20 °C View Scheme
参考文献
Wakamiya, Tateaki; Kamata, Makoto; Kusumoto, Shoichi; Kobayashi, Hiroyuki; Sai, Yoshimichi; Tamai, Ikumi; Tsuji, Akira
Bulletin of the Chemical Society of Japan, 1998 , vol. 71, # 3 p. 699 - 709
反应条件
pyridine; bis-[(trifluoroacetoxy)iodo]benzene in water; N,N-dimethyl-formamide T=0 - 20°C; Hofmann reaction; 3 h;
参考文献
Wakamiya, Tateaki; Kamata, Makoto; Kusumoto, Shoichi; Kobayashi, Hiroyuki; Sai, Yoshimichi; Tamai, Ikumi; Tsuji, Akira
Bulletin of the Chemical Society of Japan, 1998 , vol. 71, # 3 p. 699 - 709
反应条件
1: With chloroformic acid ethyl ester; triethylamine in tetrahydrofuran
T=-15°C; 0.333333 h; Inert atmosphere;
2: With ammonium hydroxide in tetrahydrofuran
T=-15 - 20°C; Inert atmosphere;
参考文献
Nahrwold, Markus; Stoncius, Arvydas; Penner, Anna; Sewald, Norbert; Neumann, Beate; Stammler, Hans-Georg
Beilstein Journal of Organic Chemistry, 2009 , vol. 5, art. no. A43
反应条件
triethylamine in N-methyl-acetamide
参考文献
Hoffmann-La Roche Inc.
Patent: US4066635 A1, 1978 ;
反应条件
ammonia in tetrahydrofuran
T=-50°C; 4 h;
参考文献
Seebach, Dieter; Boog, Alois; Schweizer, W. Bernd
European Journal of Organic Chemistry, 1999 , # 1 p. 335 - 360
参考文献
Hanson; Smith
Journal of Biological Chemistry, 1948 , vol. 175, p. 843
