3-碘代咪唑并[1,2-a]吡啶-8-羧酸甲酯合成路线 （共 3 条）
反应条件
N-iodo-succinimide in acetonitrile
T=20°C; 2 h;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; COOK, Brian Nicholas; KUZMICH, Daniel
Patent: WO2011/56440 A1, 2011 ;
Location in patent: Page/Page column 46-47 ;
WO 2011/056440 A1
反应条件
1: ethanol; water / 14 h / Reflux
2: thionyl chloride / 8 h / Reflux
3: N-iodo-succinimide / acetonitrile / 2 h / 20 °C
View Scheme
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; COOK, Brian Nicholas; KUZMICH, Daniel
Patent: WO2011/56440 A1, 2011 ;
WO 2011/056440 A1
反应条件
1: thionyl chloride / 8 h / Reflux
2: N-iodo-succinimide / acetonitrile / 2 h / 20 °C
View Scheme
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; COOK, Brian Nicholas; KUZMICH, Daniel
Patent: WO2011/56440 A1, 2011 ;
WO 2011/056440 A1
