反应条件
1: 87 percent / SOCl2, DMF / 4 h / Heating 2: CH2Cl2 / 24 h / 25 °C 3: SOCl2 / benzene / 2 h / 25 °C 4: 1.) NaH / 2.) 3 h, 90 deg C 5: 1.) Mg / 1.) Et2O <dibromoethane>, benzene, reflux, 2.) reflux, 3.25 h 6: 2.) aqueous 20 percent NaOH / 1.) 12 h, 25 deg C, 2.) MeOH, 24 h, reflux 7: BH3*THF / tetrahydrofuran / 1.a) 10 min, 0 deg C, b) 1 h, 25 deg C, 2.) THF/H2O = 2:1, 15 min, 25 deg C View Scheme
参考文献
Wilson, Janet M.; Cram, Donald J.
Journal of Organic Chemistry, 1984 , vol. 49, # 25 p. 4930 - 4943
