5,7-二羟基-2,2-二甲基-2,3-二氢-4H-苯并吡喃-4-酮合成路线 （共 12 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide T=80°C; 5 h;
参考文献
Timar, Tibor; Jaszberenyi, J. Csaba
Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 871 - 877
反应条件
1: 2: With hydrogenchloride; zinc Further stages.;
参考文献
Fang, Yu-Ting; Lin, Chia-Ning; Wu, Huan-Ting; Lee, Yean-Jang
Journal of the Chinese Chemical Society, 2007 , vol. 54, # 3 p. 817 - 822
反应条件
aluminium trichloride; trichlorophosphate
5 h; Ambient temperature;
参考文献
Jain, Niveta; Krishnamurty
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1999 , vol. 38, # 11 p. 1237 - 1241
反应条件
aluminium trichloride; trichlorophosphate
T=100°C; 1 h;
参考文献
Sowmithran, D.; Rajendra Prasad, K. J.
Synthesis, 1985 , # 5 p. 545 - 546
参考文献
Ramana, M. M. V.; Kudav, N. A.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 339 - 341
反应条件
aluminum triiodide in acetonitrile
5 h; Heating;
参考文献
Vijayalakshmi; Subramanian; Rajendra
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1990 , vol. 29, # 7 p. 661 - 663
反应条件
antimony trichloride
T=150°C;
参考文献
Miyano; Matsui
Bulletin of the Chemical Society of Japan, 1958 , vol. 31, p. 398,401
Chemische Berichte, 1958 , vol. 91, p. 2044,2045
反应条件
1.1: 70 percent / Zn powder; aq. HCl / methanol / 0 - 20 °C
2.1: Pd2(dba)3; NaOAc; formic acid / 10 h / 25 °C
2.2: 50 percent / K2CO3 / acetone / 6 h / Heating
3.1: 76 percent / DDQ / benzene / 16 h / Heating
View Scheme
参考文献
Trost, Barry M.; Toste, F. Dean; Greenman, Kevin
Journal of the American Chemical Society, 2003 , vol. 125, # 15 p. 4518 - 4526
反应条件
1.1: 70 percent / Zn powder; aq. HCl / methanol / 0 - 20 °C
2.1: Pd2(dba)3; NaOAc; formic acid / 10 h / 25 °C
2.2: 18 percent / K2CO3 / acetone / 6 h / Heating
3.1: 75 percent / DDQ / benzene / 20 h / Heating
View Scheme
参考文献
Trost, Barry M.; Toste, F. Dean; Greenman, Kevin
Journal of the American Chemical Society, 2003 , vol. 125, # 15 p. 4518 - 4526
反应条件
1: 78 percent / K2CO3, KI / dimethylformamide / 20 h / 80 °C
2: 90 percent / K2CO3 / dimethylformamide / 46 h / 80 °C
3: NaBH4 / methanol / 3 h / 40 °C
4: 4 M HCl / tetrahydrofuran / 3 h / 20 °C
View Scheme
参考文献
Timar, Tibor; Jaszberenyi, J. Csaba; Hosztafi, Sandor
Acta Chimica Hungarica, 1989 , vol. 126, # 4 p. 487 - 496
