hydrogenchloride; sodium hydrogencarbonate in acetone 0.5 h; Ambient temperature;

1: 68 percent / N-bromosuccinimide, α,α'-azobisisobutyronitrile / CCl4 / 20 h / Heating 2: 50 percent / sat. aq. sodium bicarbonate, 2N HCl / acetone / 0.5 h / Ambient temperature View Scheme

sodium hydrogencarbonate T=37°C; studiing because of the similarity to in vivo hydrolysis;