3-甲酰基-1H-吲唑-1-羧酸 1,1-二甲基乙酯合成路线 （共 6 条）
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in dichloromethane
T=0 - 20°C; 13 h;
参考文献
Crestey, Francois; Collot, Valerie; Stiebing, Silvia; Lohier, Jean-Francois; Santos, Jana Sopkova-de Oliveira; Rault, Sylvain
Tetrahedron Letters, 2007 , vol. 48, # 14 p. 2457 - 2460
反应条件
p-iodoxybenzoic acid in tetrahydrofuran
Heating;
参考文献
Foloppe, Nicolas; Fisher, Lisa M.; Francis, Geraint; Howes, Rob; Kierstan, Peter; Potter, Andrew
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 6 p. 1792 - 1804
反应条件
1: 84 percent / pyridine; EDC / tetrahydrofuran / 13.5 h / 0 - 20 °C
2: 76 percent / LiAlH4 / tetrahydrofuran / 13 h / -15 - 20 °C
3: 100 percent / triethylamine; dimethylaminopyridine / CH2Cl2 / 13 h / 0 - 20 °C
View Scheme
参考文献
Crestey, Francois; Collot, Valerie; Stiebing, Silvia; Lohier, Jean-Francois; Santos, Jana Sopkova-de Oliveira; Rault, Sylvain
Tetrahedron Letters, 2007 , vol. 48, # 14 p. 2457 - 2460
反应条件
1: 76 percent / LiAlH4 / tetrahydrofuran / 13 h / -15 - 20 °C
2: 100 percent / triethylamine; dimethylaminopyridine / CH2Cl2 / 13 h / 0 - 20 °C
View Scheme
参考文献
Crestey, Francois; Collot, Valerie; Stiebing, Silvia; Lohier, Jean-Francois; Santos, Jana Sopkova-de Oliveira; Rault, Sylvain
Tetrahedron Letters, 2007 , vol. 48, # 14 p. 2457 - 2460
反应条件
1: 60 percent / tetrahydrofuran
2: 70 percent / p-iodoxybenzoic acid / tetrahydrofuran / Heating
View Scheme
参考文献
Foloppe, Nicolas; Fisher, Lisa M.; Francis, Geraint; Howes, Rob; Kierstan, Peter; Potter, Andrew
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 6 p. 1792 - 1804
反应条件
1: 60 percent / tetrahydrofuran
2: 70 percent / p-iodoxybenzoic acid / tetrahydrofuran / Heating
View Scheme
参考文献
Foloppe, Nicolas; Fisher, Lisa M.; Francis, Geraint; Howes, Rob; Kierstan, Peter; Potter, Andrew
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 6 p. 1792 - 1804
