2,5-二氯-3-硝基苯甲酸合成路线 （共 6 条）
反应条件
1: With sulfuric acid T=-10°C; 0.166667 h; 2: With nitric acid T=-10°C; 2 h;
参考文献
EPIZYME, INC.; EISAI CO., LTD.; KUNTZ, Kevin, Wayne; CHESWORTH, Richard; DUNCAN, Kenneth, William; KEILHACK, Heike; WARHOLIC, Natalie; KLAUS, Christine; ZHENG, Wanjun
Patent: WO2012/142513 A1, 2012 ;
Location in patent: Page/Page column 280 ;
WO 2012/142513 A1
反应条件
in sodium hydrogencarbonate; dimethyl sulfoxide
参考文献
Amchem Products Inc.
Patent: US4252979 A1, 1981 ;
反应条件
alkaline permanganate
参考文献
Journal of the Chemical Society, , p. 2381
反应条件
1: beim Nitrieren 2: alkaline permanganate View Scheme
参考文献
Journal of the Chemical Society, , p. 2381
反应条件
hydrogenchloride; RaNi in methanol
参考文献
EPIZYME, INC.; EISAI CO., LTD.; KUNTZ, Kevin, Wayne; CHESWORTH, Richard; DUNCAN, Kenneth, William; KEILHACK, Heike; WARHOLIC, Natalie; KLAUS, Christine; ZHENG, Wanjun
Patent: WO2012/142513 A1, 2012 ;
WO 2012/142513 A1
参考文献
GAF Corporation
Patent: US3931303 A1, 1976 ;
