2-氨基-4-氯-5-甲基苯磺酸合成路线 （共 6 条）
反应条件
chlorosulphuric acid
参考文献
I. G. Farbenind.
Patent: DE526171 , 1929 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 17, p. 521
Full Text Show Details
Gen. Aniline Works
Patent: US1911719 , 1930 ;
反应条件
1: N,N-dimethyl acetamide / |Reflux 2: |Heating View Scheme
参考文献
Bekoe, Sandor L.; Bats, Jan W.; Alig, Edith; Schmidt, Martin U.
Journal of Chemical Crystallography, 2013 , vol. 43, # 12 p. 655 - 663
反应条件
1: 2-amino-4-chloro-5-methylbenzene sulfonic acid With sodium hydroxide in water 2: With hydrogenchloride; sodium acetate; sodium nitrite in water T=10°C; pH=3 - 4; 3: 3-hydroxy-5,6,7,8-tetrahydro-2-naphthoic acid in water T=15 - 60°C; 3.5 h;
参考文献
Clariant Finance (BVI) Limited
Patent: US7892344 B2, 2011 ;
Location in patent: Page/Page column 20 ;
反应条件
(i) ClSO3H, NaCl, (heating), (ii) aq. NH3; Multistep reaction;
参考文献
Novello,F.C. et al.
Journal of Organic Chemistry, 1960 , vol. 25, p. 965 - 970
