2-溴-3-(4-溴苯基)-3-氧代-丙酸乙酯合成路线 （共 3 条）
反应条件
in ethanol T=75°C; 2 h;
参考文献
INTERMUNE, INC.; BUCKMAN, Brad, O.; NICHOLAS, John, B.; EMAYAN, Kumaraswamy; SEIWERT, Scott, D.
Patent: WO2013/25733 A1, 2013 ;
Location in patent: Paragraph 0673 ;
反应条件
N-bromosuccinmide in dichloromethane
18 h;
参考文献
Bristol-Myers Squibb Company
Patent: US2008/44380 A1, 2008 ;
Location in patent: Page/Page column 158 ;
反应条件
1: sodium hydride / toluene / Reflux; Inert atmosphere
2: bromine / chloroform
View Scheme
参考文献
Zhang, Kai; Tieke, Bernd; Forgie, John C.; Vilela, Filipe; Parkinson, John A.; Skabara, Peter J.
Polymer, 2010 , vol. 51, # 26 p. 6107 - 6114
