5-溴-2-(4-BOC-哌嗪-1-基)-3-甲基吡啶合成路线 (共 2 条)
反应条件
N-ethyl-N,N-diisopropylamine in N,N-dimethyl acetamide T=130°C; 36 h;
参考文献
WO2006/26135 A2, ;
Page/Page column 76 ;
WO 2006/026135 A2
反应条件
potassium fluoride; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct in tetrahydrofuran Suzuki coupling; 2 h; Inert atmosphereReflux; regioselective reaction;
参考文献
Tetrahedron, , vol. 66, # 49 p. 9552 - 9559