2-苯基-5,6-二氢咪唑并[2,1-a]异喹啉合成路线 （共 14 条）
反应条件
hydrogen; palladium on activated charcoal in ethanol; acetic acid
T=90°C; P=7500.6 Torr; 3 h;
参考文献
Toja; Omodei Sale; Favara; Omodei-Sale; Cattaneo; Gallico; Galliani
Arzneimittel-Forschung/Drug Research, 1983 , vol. 33, # 9 p. 1222 - 1226
反应条件
ethylenediaminetetraacetic acid; mercury(II) oxide in ethanol
T=80 - 90°C; 9 h;
参考文献
Mohrle; Grimm
Archiv der Pharmazie, 1986 , vol. 319, # 9 p. 774 - 787
反应条件
1: 64 percent / 2.) 70percent HClO4 / 1.) ether, room temp., 24 h
2: 65 percent / H2NOH*HCl, CH3COONa / aq. acetic acid
View Scheme
参考文献
Mohrle; Grimm
Archiv der Pharmazie, 1986 , vol. 319, # 4 p. 325 - 332
反应条件
1: diethyl ether
2: 83 percent / HgO/EDTA / aq. ethanol
3: acetic anhydride / 12 h / Ambient temperature
View Scheme
参考文献
Mohrle; Grimm
Archiv der Pharmazie, 1986 , vol. 319, # 9 p. 774 - 787
反应条件
1: diethyl ether
2: 83 percent / HgO/EDTA / aq. ethanol
3: acetic anhydride / 12 h / Ambient temperature
View Scheme
参考文献
Mohrle; Grimm
Archiv der Pharmazie, 1986 , vol. 319, # 9 p. 774 - 787
反应条件
1: 69 percent / 1.) 15 min., room temp., CHCl3, 2.) 15 min., heating on a steam bath
2: 74 percent / H2 / 10percent Pd/C / ethanol; acetic acid / 3 h / 90 °C / 7500.6 Torr
View Scheme
参考文献
Toja; Omodei Sale; Favara; Omodei-Sale; Cattaneo; Gallico; Galliani
Arzneimittel-Forschung/Drug Research, 1983 , vol. 33, # 9 p. 1222 - 1226
反应条件
1: FeCl3, AcONH4 / acetic acid / 6 h / 150 °C
2: 74 percent / H2 / 10percent Pd/C / ethanol; acetic acid / 3 h / 90 °C / 7500.6 Torr
View Scheme
参考文献
Toja; Omodei Sale; Favara; Omodei-Sale; Cattaneo; Gallico; Galliani
Arzneimittel-Forschung/Drug Research, 1983 , vol. 33, # 9 p. 1222 - 1226
反应条件
1: HgO/EDTA / aq. ethanol
2: acetic anhydride / 12 h / Ambient temperature
View Scheme
参考文献
Mohrle; Grimm
Archiv der Pharmazie, 1986 , vol. 319, # 9 p. 774 - 787
反应条件
1: 74 percent / hydroxylamine hydrochloride / ethanol / 3 h / Heating
2: 83 percent / HgO/EDTA / aq. ethanol
3: acetic anhydride / 12 h / Ambient temperature
View Scheme
参考文献
Mohrle; Grimm
Archiv der Pharmazie, 1986 , vol. 319, # 9 p. 774 - 787
反应条件
1: 83 percent / HgO/EDTA / aq. ethanol
2: acetic anhydride / 12 h / Ambient temperature
View Scheme
参考文献
Mohrle; Grimm
Archiv der Pharmazie, 1986 , vol. 319, # 9 p. 774 - 787
