3-(7-氯吡唑并[1,5-a]嘧啶-5-基)哌啶-1-羧酸叔丁酯合成路线 (共 2 条)
反应条件
trichlorophosphate in N,N-dimethyl-aniline
T=25°C; 96 h; Product distribution / selectivity;
参考文献
Labroli, Marc; Paruch, Kamil; Dwyer, Michael P.; Alvarez, Carmen; Keertikar, Kartik; Poker, Cory; Rossman, Randall; Duca, Jose S.; Fischmann, Thierry O.; Madison, Vincent; Parry, David; Davis, Nicole; Seghezzi, Wolfgang; Wiswell, Derek; Guzi, Timothy J.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 1 p. 467 - 470
反应条件
ammonia in water; isopropyl alcohol
T=70°C; 28 h; Product distribution / selectivity;
参考文献
Labroli, Marc; Paruch, Kamil; Dwyer, Michael P.; Alvarez, Carmen; Keertikar, Kartik; Poker, Cory; Rossman, Randall; Duca, Jose S.; Fischmann, Thierry O.; Madison, Vincent; Parry, David; Davis, Nicole; Seghezzi, Wolfgang; Wiswell, Derek; Guzi, Timothy J.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 1 p. 467 - 470