5'-碘-1,1':3',1''-三联苯合成路线 （共 13 条）
反应条件
copper T=250 - 280°C; 3 h;
参考文献
Chemical & Pharmaceutical Bulletin, , vol. 31, # 7 p. 2313 - 2320
反应条件
copper T=250 - 280°C; 3 h;
参考文献
Chemical & Pharmaceutical Bulletin, , vol. 31, # 7 p. 2313 - 2320
反应条件
copper T=260 - 270°C; 3 h;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 31, # 5 p. 1572 - 1581
反应条件
1: With n-butyllithium in diethyl ether; hexane; toluene T=-30 - 0°C; 1 h; 2: With tri-isopropoxy-borane in diethyl ether; hexane; toluene 3: With hydrogenchloride; water in diethyl ether; hexane; toluene
参考文献
IDEMITSU KOSAN CO., LTD.
Patent: EP1864965 A1, 2007 ;
Location in patent: Page/Page column 25 ;
反应条件
1: iode-3,5-diphenylbenzene With n-butyllithium in tetrahydrofuran; hexane T=-40 - 0°C; 1 h; Inert atmosphere; 2: boric acid trimethyl ester in tetrahydrofuran; hexane T=-78 - 20°C; 5 h; Inert atmosphere; 3: With hydrogenchloride in tetrahydrofuran; hexane; water
参考文献
Mitsui Chemicals, Inc.
Patent: EP2348017 A1, 2011 ;
Location in patent: Page/Page column 48-49 ;
反应条件
sulfuric acid; water; hydrogen iodide; iodine in acetic acid
T=70°C; 3 h;
参考文献
IDEMITSU KOSAN CO., LTD.
Patent: WO2006/73054 A1, 2006 ;
Location in patent: Page/Page column 59-60 ;
反应条件
sulfuric acid; iodine; acetic acid in methanol
参考文献
IDEMITSU KOSAN CO., LTD.
Patent: EP1834946 A1, 2007 ;
参考文献
MITSUI CHEMICALS, INC.
Patent: US2011/198581 A1, 2011 ;
反应条件
1: 24 percent / copper powder
2: 96 percent / activated iron, hydrogen chloride / benzene
3: 1.) natrium nitrite, concetrated sulfuric acid; 2.) potassium iodide
View Scheme
参考文献
Ozasa, Shigeru; Fujioka, Yasuhiro; Kikutake, Jun-ichiro; Ibuki, Eiichi
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 5 p. 1572 - 1581
反应条件
1: 1.) sodium nitrite, concentrated sulfuric acid; 2.) Gattermann copper
2: 24 percent / copper powder
3: 96 percent / activated iron, hydrogen chloride / benzene
4: 1.) natrium nitrite, concetrated sulfuric acid; 2.) potassium iodide
View Scheme
参考文献
Ozasa, Shigeru; Fujioka, Yasuhiro; Kikutake, Jun-ichiro; Ibuki, Eiichi
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 5 p. 1572 - 1581
