5-氟-1H-吲哚-7-羧酸合成路线 （共 3 条）
反应条件
1: 7-bromo-5-fluoroindole With sec.-butyllithium in tetrahydrofuran; cyclohexane T=-75°C; 2: carbon dioxide in tetrahydrofuran; cyclohexane cooling;
参考文献
Schlosser, Manfred; Ginanneschi, Assunta; Leroux, Frederic
European Journal of Organic Chemistry, 2006 , # 13 p. 2956 - 2969
反应条件
1.1: 76 percent / nitric acid; sulfuric acid; water / 0 °C 2.1: 57 percent / tetrahydrofuran / -40 °C 3.1: sec-butyllithium / cyclohexane; tetrahydrofuran / -75 °C 3.2: 54 percent / cyclohexane; tetrahydrofuran / cooling View Scheme
参考文献
European Journal of Organic Chemistry, , # 13 p. 2956 - 2969
反应条件
1.1: 57 percent / tetrahydrofuran / -40 °C 2.1: sec-butyllithium / cyclohexane; tetrahydrofuran / -75 °C 2.2: 54 percent / cyclohexane; tetrahydrofuran / cooling View Scheme
参考文献
European Journal of Organic Chemistry, , # 13 p. 2956 - 2969
