3,5-二氯-1-甲基吡嗪-2(1H)-酮合成路线 （共 2 条）
反应条件
in 1,2-dichloro-benzene
T=80°C; 8 h;
参考文献
PIERRE FABRE MEDICAMENT; Leroy, Isabelle; Dupont-Passelaigue, Elisabeth; Mialhe, Samuel; Junquero, Didier; Valeille, Karine
Patent: US2013/40928 A1, 2013 ;
Location in patent: Paragraph 0245; 0246; 0247 ;
反应条件
1: KOH / dioxane; H2O
2: 34 percent / diethyl ether; methanol / 24 h
View Scheme
参考文献
Vekemans; Pollers Wieers; Hoornaert
Journal of Heterocyclic Chemistry, 1983 , vol. 20, # 4 p. 919 - 923
