3-氨基-5,5-二甲基-2-环己烯-1-酮合成路线 （共 39 条）
反应条件
sodium hydride 1.)dioxane,reflux,1 h 2.)2 eq iodomethane,reflux,1-2 h; Yield given. Multistep reaction;
参考文献
Greenhill, John V.; Moten, Ashraf M.
Tetrahedron, 1983 , vol. 39, # 20 p. 3405 - 3408
反应条件
sodium hydride in 1,4-dioxane HeatingEffect of solvents, ratio of reagents and reflux period. Other enaminones were also investigated.; Product distribution;
参考文献
Greenhill, John V.; Moten, Ashraf M.
Tetrahedron, 1983 , vol. 39, # 20 p. 3405 - 3408
反应条件
copper acetylacetonate in dichloromethane 24 h; Heating;
参考文献
Eberlin, Marcos N.; Kascheres, Concetta
Journal of Organic Chemistry, 1988 , vol. 53, # 9 p. 2084 - 2086
反应条件
caesium carbonate; N-[2'-(dicyclohexylphosphino)-1,1'-biphenyl-2-yl]-N,N-dimethylamine; tris(dibenzylideneacetone)dipalladium (0) in tetrahydrofuran
T=80°C; Arylation; 24 h;
参考文献
Edmondson, Scott D.; Mastracchio, Anthony; Parmee, Emma R.
Organic Letters, 2000 , vol. 2, # 8 p. 1109 - 1112
参考文献
Haas
Journal of the Chemical Society, 1906 , vol. 89, p. 200
反应条件
tris(dibenzylideneacetone)dipalladium (0); caesium carbonate; N-[2'-(dicyclohexylphosphino)-1,1'-biphenyl-2-yl]-N,N-dimethylamine in tetrahydrofuran
T=80°C; Arylation; 14 h;
参考文献
Edmondson, Scott D.; Mastracchio, Anthony; Parmee, Emma R.
Organic Letters, 2000 , vol. 2, # 8 p. 1109 - 1112
反应条件
tris(dibenzylideneacetone)dipalladium (0); caesium carbonate; N-[2'-(dicyclohexylphosphino)-1,1'-biphenyl-2-yl]-N,N-dimethylamine in tetrahydrofuran
T=80°C; Arylation; 24 h;
参考文献
Edmondson, Scott D.; Mastracchio, Anthony; Parmee, Emma R.
Organic Letters, 2000 , vol. 2, # 8 p. 1109 - 1112
反应条件
in water
Diels-Alder reaction; Heating;
参考文献
Bilbao, Estibaliz R.; Alvarado, Mario; Masaguer, Christian F.; Ravina, Enrique
Tetrahedron Letters, 2002 , vol. 43, # 19 p. 3551 - 3554
反应条件
acetic acid
Condensation; Heating;
参考文献
Pyrko
Chemistry of Heterocyclic Compounds, 1999 , vol. 35, # 6 p. 688 - 694
反应条件
sodium hydride
1.)toluene,reflux,3 h 2.)1 eq iodomethane,reflux,1-2 h; Yield given. Multistep reaction;
参考文献
Greenhill, John V.; Moten, Ashraf M.
Tetrahedron, 1983 , vol. 39, # 20 p. 3405 - 3408
