1: 93 percent / pyridine / 0.17 h / 0 - 10 °C
2: 62 percent / KF, CuI / dimethylformamide / 10 h / 100 °C
View Scheme
参考文献
Duan, Jian-Xing; Chen, Quing-Yun
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 6 p. 725 - 730
1: 4-chloro-1-hydroxymethyl-benzene With trifluoromethylsulfonic anhydride; bis-(phenyl)-sulfoxide; N,N,N',N'-tetra-methylnaphthalene-1,8-diamine in toluene
T=-78°C;
2: sodium salt of dimethylmalonate in tetrahydrofuran; toluene
T=-78 - 20°C;
参考文献
Takuwa, Tomofumi; Minowa, Tomofumi; Fujisawa, Hidehiko; Mukaiyama, Teruaki
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 5 p. 476 - 480
