3-(2-脱氧-alpha-D-赤式-呋喃戊糖基)嘧啶并[1,2-a]嘌呤-10(3H)-酮合成路线 (共 10 条)
反应条件
borate-phosphate-citrate universal buffer in acetonitrile T=20°C; pH=7; 15 h; Product distributionKinetics; Further Variations:pH-valuesTemperatures;
参考文献
Otteneder, Michael; Plastaras, John P.; Marnett, Lawrence J.
Chemical Research in Toxicology, 2002 , vol. 15, # 3 p. 312 - 318
反应条件
borate-phosphate-citrate universal buffer in acetonitrile T=20°C; pH=7.0; 15 h; Product distribution;
参考文献
Otteneder, Michael; Plastaras, John P.; Marnett, Lawrence J.
Chemical Research in Toxicology, 2002 , vol. 15, # 3 p. 312 - 318
反应条件
borate-phosphate-citrate universal buffer in acetonitrile T=20°C; pH=7.0; 15 h; Product distribution;
参考文献
Otteneder, Michael; Plastaras, John P.; Marnett, Lawrence J.
Chemical Research in Toxicology, 2002 , vol. 15, # 3 p. 312 - 318
反应条件
borate-phosphate-citrate universal buffer in acetonitrile T=20°C; pH=7.0; 15 h; Product distribution;
参考文献
Chemical Research in Toxicology, , vol. 15, # 3 p. 312 - 318
反应条件
borate-phosphate-citrate universal buffer in acetonitrile T=20°C; pH=7.0; 15 h; Product distribution;
参考文献
Otteneder, Michael; Plastaras, John P.; Marnett, Lawrence J.
Chemical Research in Toxicology, 2002 , vol. 15, # 3 p. 312 - 318
反应条件
2-(n-morpholino)ethanesulfonic acid; nucleoside 2-deoxyribosyltransferase (EC 2.4.2.6) in methanol
T=37°C; pH=6.0; 2 h;
参考文献
Schnetz-Boutaud, Nathalie C.; Mao, Hui; Stone, Michael P.; Marnett, Lawrence J.
Chemical Research in Toxicology, 2000 , vol. 13, # 2 p. 90 - 95
反应条件
dipotassium hydrogenphosphate in water
T=37°C; 240 h;
参考文献
Seto, Hiroshi; Okuda, Taisuke; Takesue, Tomoyuki; Ikemura, Tadashi
Bulletin of the Chemical Society of Japan, 1983 , vol. 56, # 6 p. 1799 - 1802
反应条件
1: aq. HCl / 0.5 h / 70 °C
2: trans-N-deoxyribosylase; MES / H2O / 2 h / 37 °C / Enzymatic reaction
View Scheme
参考文献
Jeong, Yo-Chan; Sangaiah, Ramiah; Nakamura, Jun; Pachkowski, Brian F.; Ranasinghe, Asoka; Gold, Avram; Ball, Louise M.; Swenberg, James A.
Chemical Research in Toxicology, 2005 , vol. 18, # 1 p. 51 - 60
反应条件
1: aq. HCl / methanol / 0.5 h / 70 °C
2: 220 mg / 2-(N-morpholino)-ethanesulfonic acid; nucleoside 2-deoxyribosyltransferase (EC 2.4.2.6) / methanol / 2 h / 37 °C / pH 6.0
View Scheme
参考文献
Schnetz-Boutaud, Nathalie C.; Mao, Hui; Stone, Michael P.; Marnett, Lawrence J.
Chemical Research in Toxicology, 2000 , vol. 13, # 2 p. 90 - 95
反应条件
trans-N-deoxyribosylase from Lactobacillus helveticus in water
T=37°C; trans-deoxyribosylation; 15 h; Enzymatic reactionproduct analyzed by HPLC; Product distribution;
参考文献
Mueller, Michael; Hutchinson, Linda K.; Peter Guengerich
Chemical Research in Toxicology, 1996 , vol. 9, # 7 p. 1140 - 1144