1: 84 percent / K2CO3 / dimethylformamide / 8 h / Ambient temperature 2: 97 percent / pyridine / 6 h / Ambient temperature 3: 90 percent / 48 h / Ambient temperature; Candida cylindraceae lipase, 0.1M sodium phosphate buffer (pH 7) 4: 89 percent / H2 / 5percent Pd/C / ethyl acetate / 0.5 h / Ambient temperature View Scheme

1: 84 percent / K2CO3 / dimethylformamide / 8 h / Ambient temperature 2: 97 percent / pyridine / 6 h / Ambient temperature 3: 90 percent / 48 h / Ambient temperature; Candida cylindraceae lipase, 0.1M sodium phosphate buffer (pH 7) 4: 89 percent / H2 / 5percent Pd/C / ethyl acetate / 0.5 h / Ambient temperature 5: 73 percent / CF3COOH / 0.5 h / 0 °C View Scheme

1: 84 percent / K2CO3 / dimethylformamide / 8 h / Ambient temperature 2: 97 percent / pyridine / 6 h / Ambient temperature 3: 90 percent / 48 h / Ambient temperature; Candida cylindraceae lipase, 0.1M sodium phosphate buffer (pH 7) 4: 89 percent / H2 / 5percent Pd/C / ethyl acetate / 0.5 h / Ambient temperature 5: 73 percent / CF3COOH / 0.5 h / 0 °C View Scheme