2-二乙氨基氯乙烷盐酸盐合成路线 （共 91 条）
反应条件
1: 4 h; Reflux; 2: With thionyl chloride in tetrachloromethane T=20°C; 4 h;
参考文献
CHINA PHARMACEUTICAL UNIVERSITY; Xiang, Hua; Wang, Tianlin; Xiao, Hong; You, Qidong; Yao, Yao; Li, Xiaobo; Liao, Qingjiang
Patent: US2013/85140 A1, 2013 ;
Location in patent: Paragraph 0060; 0061 ;
反应条件
thionyl chloride; chloroform T=-5°C;
参考文献
Journal of the Chemical Society, , p. 2443
参考文献
Li, Xuyuan; Meng, Yanfa; Zhao, Kehao; Tu, Weixia
ACH - Models in Chemistry, 1997 , vol. 134, # 4 p. 383 - 393
反应条件
sodium carbonate in N,N-dimethyl-formamide T=33°C; Decomposition; Equilibrium constant;
参考文献
International Journal of Chemical Kinetics, , vol. 26, # 2 p. 309 - 315
反应条件
sodium hydride 1.) DMF, 90 deg C, 1 h, 2.) DMF, 90 deg C, 3 h; Multistep reaction;
参考文献
Prasad, Mohan; Rastogi, Shri Nivas; Kar, K.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 729 - 734
反应条件
potassium carbonate; acetone
参考文献
Harsanyi,K. et al.
Journal of Medicinal Chemistry, 1964 , vol. 7, p. 623 - 625
反应条件
potassium carbonate; potassium hydroxide in acetone 3 h; Reflux;
参考文献
Di Braccio, Mario; Grossi, Giancarlo; Signorello, Maria Grazia; Leoncini, Giuliana; Cichero, Elena; Fossa, Paola; Alfei, Silvana; Damonte, Gianluca
European Journal of Medicinal Chemistry, 2013 , vol. 62, p. 564 - 578
反应条件
1: 67 percent / aq. KOH / 4 h / 60 - 70 °C 2: 61 percent / aq. NH3 / 2 h / 140 - 160 °C View Scheme
参考文献
Divaeva; Kuzmenko; Morkovnik; Komissarov
Chemistry of Heterocyclic Compounds, 2006 , vol. 42, # 4 p. 463 - 468
反应条件
potassium carbonate; toluene
参考文献
Kung; Chang
Huaxue Xuebao, 1956 , vol. 22, p. 467,470
Chem.Abstr., 1958 , p. 10971
反应条件
potassium carbonate in N-methyl-acetamide; water
参考文献
Dr. Karl Thomae GmbH
Patent: US5919807 A1, 1999 ;
