1-叠氮基-3,6,9-三氧杂十一烷-11-醇合成路线 （共 26 条）
反应条件
1: 88 percent / triethylamine / CH2Cl2 / 24 h / 20 °C 2: 70 percent / dimethylformamide / 12 h / 120 °C 3: 92 percent / hydrazine hydrate / ethanol / 24 h / 80 °C View Scheme
参考文献
Goswami, Lalit N.; Houston, Zachary H.; Sarma, Saurav J.; Jalisatgi, Satish S.; Hawthorne, M. Frederick
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 7 p. 1116 - 1126
反应条件
1.1: 92 percent / Et3N / CH2Cl2 / 0.83 h / 0 - 20 °C 2.1: NaH / dimethylformamide / 0.5 h / 20 °C 2.2: dimethylformamide / 22 h / 20 °C 3.1: 0.51 g / p-TsOH / methanol 4.1: Ph3P / tetrahydrofuran / 20 h / 20 °C 4.2: 90 percent / H2O / tetrahydrofuran View Scheme
参考文献
Svedhem; Hollander; Shi; Konradsson; Liedberg; Svensson
Journal of Organic Chemistry, 2001 , vol. 66, # 13 p. 4494 - 4503
反应条件
chromium(VI) oxide; sulfuric acid in water; acetone T=0 - 20°C;
参考文献
Liao, Longyan; Liu, Jenny; Dreaden, Erik C.; Morton, Stephen W.; Shopsowitz, Kevin E.; Hammond, Paula T.; Johnson, Jeremiah A.
Journal of the American Chemical Society, 2014 , vol. 136, # 16 p. 5896 - 5899
反应条件
1: 80 percent / CrO3; aq. H2SO4 / acetone 2: 100 percent / H2 / Pd/C / ethanol View Scheme
参考文献
Nakatani, Kazuhiko; Kobori, Akio; Kumasawa, Hiroyuki; Saito, Isao
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 5 p. 1105 - 1108
反应条件
triethylamine in dichloromethane
Inert atmosphere;
参考文献
Yue, Xuyi; Feng, Yue; Yu, Y. Bruce
Journal of Fluorine Chemistry, 2013 , vol. 152, p. 173 - 181
反应条件
1: palladium on carbon; hydrogen / tetrahydrofuran
2: dichloromethane
3: sodium hydroxide / tetrahydrofuran; toluene / 45 °C
4: hydrogenchloride; water / 1 h
5: potassium carbonate / water / 16.75 h / 20 °C
View Scheme
参考文献
Schmidt, Florian; Rosnizeck, Ina C.; Spoerner, Michael; Kalbitzer, Hans Robert; Koenig, Burkhard
Inorganica Chimica Acta, 2011 , vol. 365, # 1 p. 38 - 48
