1-叠氮基-3,6,9-三氧杂十一烷-11-醇合成路线 （共 26 条）
反应条件
1: Et3N / 3 h / Ambient temperature 2: 73 percent / NaN3 / aq. ethanol / 8 h / Heating 3: 80 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 2 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 56, # 13 p. 4326 - 4329
反应条件
1: 73 percent / NaN3 / aq. ethanol / 8 h / Heating 2: 80 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 2 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 56, # 13 p. 4326 - 4329
反应条件
sodium azide in ethanol Reflux;
参考文献
Muehlberg, Michaela; Siebertz, Kristina D.; Schlegel, Brigitte; Schmieder, Peter; Hackenberger, Christian P.R.
Chemical Communications, 2014 , vol. 50, # 35 p. 4603 - 4606
反应条件
sodium azide; triethylamine 1) ether, 0 deg C to r.t., 2) aq. EtOH, 24 h, reflux; Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 56, # 13 p. 4326 - 4329
反应条件
1.1: 92 percent / Et3N / CH2Cl2 / 0.83 h / 0 - 20 °C 2.1: NaH / dimethylformamide / 0.5 h / 20 °C 2.2: dimethylformamide / 22 h / 20 °C 3.1: 0.51 g / p-TsOH / methanol View Scheme
参考文献
Svedhem; Hollander; Shi; Konradsson; Liedberg; Svensson
Journal of Organic Chemistry, 2001 , vol. 66, # 13 p. 4494 - 4503
反应条件
water; triphenylphosphine in tetrahydrofuran 4 h; Ambient temperature;
参考文献
WISCONSIN ALUMNI RESEARCH FOUNDATION
Patent: WO2009/132310 A1, 2009 ;
Location in patent: Page/Page column 66 ;
反应条件
1: 1-azido-11-hydroxy-3,6,9-trioxaundecane With triphenylphosphine in tetrahydrofuran T=0 - 20°C; 12 h; 2: water 12 h;
参考文献
Aleman Garcia, Miguel A.; Bampos, Nick
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 1 p. 27 - 30
反应条件
triphenylphosphine in tetrahydrofuran; pyridine; water
参考文献
Cetus Corporation
Patent: US4705886 A1, 1987 ;
反应条件
hydrogen; 10percent Pd/C in ethyl acetate
参考文献
Ling, Frank H.; Lu, Victor; Svec, Frantisek; Frechet, Jean M. J.
Journal of Organic Chemistry, 2002 , vol. 67, # 7 p. 1993 - 2002
反应条件
1: 100 percent / triphenylphosphine, H2O / tetrahydrofuran / 4 h / Ambient temperature 2: 90 percent / KOH / H2O; dioxane / 1) 0 deg C, 1 h, 2) room temp., 4 h View Scheme
参考文献
Pokorski, Jonathan K.; Breitenkamp, Kurt; Liepold, Lars O.; Qazi, Shefah; Finn
Journal of the American Chemical Society, 2011 , vol. 133, # 24 p. 9242 - 9245
