S-甲基异硫脲半硫酸盐合成路线 （共 119 条）
反应条件
in ethanol Heating10-12 h; Yield given;
参考文献
Journal of Heterocyclic Chemistry, , vol. 27, # 7 p. 1885 - 1892
反应条件
sodium hydrogencarbonate in dichloromethane 38.4 h;
参考文献
Bergeron, Raymond J.; McManis, James S.
Journal of Organic Chemistry, 1987 , vol. 52, # 9 p. 1700 - 1703
反应条件
1: 2-methyl-2-thiopseudourea sulfate; methyl chloroformate With sodium hydroxide in water T=3 - 6°C; 0.666667 h; 2: 1,2-diamino-4-phenylthiobenzene With acetic acid in ethanol; water T=95°C; 24 h;
参考文献
Cortes, Eduardo Cortes; Mendoza, Rafael Sosa; Gutierrez, Maximiliano Santibanez; De Cortes, Olivia Garcia-Mellado
Journal of Heterocyclic Chemistry, 2004 , vol. 41, # 2 p. 273 - 276
反应条件
sodium acetate in acetic acid 8 h; Heating / reflux;
参考文献
GLAXO GROUP LIMITED
Patent: WO2005/48999 A2, 2005 ;
Location in patent: Page/Page column 27 ;
参考文献
Short,J.H. et al.
J. Med. Chem., 1963 , vol. 6, p. 275 - 283
反应条件
triethylamine in ethanol; water T=30°C; 6 h; Green chemistry;
参考文献
RSC Advances, , vol. 3, # 38 p. 17150 - 17155
反应条件
in water 1 h; Heating;
参考文献
Lee, Young Bok; Park, Myung Hee; Folk, J. E.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 16 p. 3053 - 3061
反应条件
pyridine in water 36 h; Heating;
参考文献
Madruga, Claudia da C.; Clerici, Edflia; Martins, Marcos A. P.; Zanatta, Nilo
Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 3 p. 735 - 738
参考文献
Short,J.H. et al.
J. Med. Chem., 1963 , vol. 6, p. 275 - 283
参考文献
Short,J.H. et al.
J. Med. Chem., 1963 , vol. 6, p. 275 - 283
