5-氧代-4,5,6,7-四氢吡唑并[1,5-a]吡啶-3-羧酸甲酯合成路线 （共 3 条）
反应条件
Dess-Martin periodane in dichloromethane
T=20°C; 2 h;
参考文献
Elsner, Jan; Boeckler, Frank; Heinemann, Frank W.; Huebner, Harald; Gmeiner, Peter
Journal of Medicinal Chemistry, 2005 , vol. 48, # 18 p. 5771 - 5779
反应条件
1: 75 percent / H2 / Pd/C / ethanol / 48 h / 80 °C / 15001.2 Torr
2: 70 percent / Dess-Martin periodinane / CH2Cl2 / 2 h / 20 °C
View Scheme
参考文献
Elsner, Jan; Boeckler, Frank; Heinemann, Frank W.; Huebner, Harald; Gmeiner, Peter
Journal of Medicinal Chemistry, 2005 , vol. 48, # 18 p. 5771 - 5779
反应条件
1: CH2Cl2 / 0 - 20 °C
2: 6.3 g / K2CO3 / dimethylformamide / 16 h / 20 °C
3: 75 percent / H2 / Pd/C / ethanol / 48 h / 80 °C / 15001.2 Torr
4: 70 percent / Dess-Martin periodinane / CH2Cl2 / 2 h / 20 °C
View Scheme
参考文献
Elsner, Jan; Boeckler, Frank; Heinemann, Frank W.; Huebner, Harald; Gmeiner, Peter
Journal of Medicinal Chemistry, 2005 , vol. 48, # 18 p. 5771 - 5779
