sodium hydroxide T=80°C; 2 h;

sodium methylate in N-methyl-acetamide; methanol; water

1: 110 °C 2: aq. NaOH / methanol / Heating View Scheme

lithium aluminium tetrahydride in tetrahydrofuran T=0°C; 22 h;

sodium hydroxide in tetrahydrofuran T=40°C; 5 h;

sodium hydroxide; sodium nitrite in water; acetic acid

sodium hydroxide in methanol; water

2: 110 °C 3: aq. NaOH / methanol / Heating View Scheme

1: HNO3 / Heating 3: 110 °C 4: aq. NaOH / methanol / Heating View Scheme

1: 84 percent / anh. potassium carbonate / acetone / 34 h / Heating 2: 20 percent / sodium ethoxide / ethanol / 0.5 h / Heating 3: 92 percent / sulfuric acid / 4 h / Heating 4: 70 percent / p-toluenesulfonic acid monohydrate / toluene / 9 h / Heating 5: 81 percent / hydrogen / 10percent Pd/C / acetic acid / 12 h / 2844.3 Torr / Ambient temperature 6: 88 percent / phosphoryl chloride / 1 h / 120 °C 7: 80 percent / sodium methoxide / methanol / 5 h / Heating 8: 50 percent / lithium aluminum hydride / tetrahydrofuran / 22 h / 0 °C View Scheme