反应条件
1.1: 93 percent / 4-N,N-dimethylaminopyridine; pyridine / CH2Cl2 / 2 h / 20 °C 2.1: [(ν3-C3H5)PdCl]2; (1S,2S)-bis(N,N'-(o-(PPh2)C6H4CO)-1,2-diphenylethylamine; Et3N / CH2Cl2 / 8 h / 20 °C 3.1: TsOH*H2O / methanol / 4 h / 50 °C 4.1: DIBAlH / toluene; hexane / 1.5 h / -78 °C 5.1: Ph3P; diisopropylazodicarboxylate / diethyl ether / 0.33 h / -20 °C 5.2: diethyl ether / 12 h / -20 - 20 °C 5.3: 1.34 g / aq. TsOH / tetrahydrofuran / 4 h / 20 °C 6.1: 91 percent / Pd(OAc)2; Ag2CO3; diphenylphosphinopropane / 1,3-bis(diphenylphosphino)propane / toluene / 24 h / 107 °C 7.1: 91 percent / PPh3 / CH2Cl2 / 0.17 h / 0 °C 8.1: 88 percent / Pd(PPh3)4; Bu3SnH / toluene / 0.33 h 9.1: 65 percent / Pd(OAc)2; Ag2CO3; diphenylphosphinopropane / 1,3-bis(diphenylphosphino)propane / toluene / 4 h / 107 °C 10.1: SeO2; quartz sand / dioxane / 1.33 h / 75 °C 11.1: DIBALH / CH2Cl2; hexane; diethyl ether / -78 - 0 °C 11.2: NH4Br / various solvents / 2 h / 20 °C 11.3: 89 percent / NaBH4 / various solvents / 20 °C 12.1: LDA / tetrahydrofuran; hexane / -78 - 20 °C 12.2: 57 percent / tetrahydrofuran; hexane / 6 h / 20 °C / Irradiation 13.1: BBr3 View Scheme
参考文献
Journal of the American Chemical Society, , vol. 127, # 42 p. 14785 - 14803
