1-[(2-甲基-2-丙基)氨基]-3-[(5-甲基-3-噻吩基)氧基]-2-丙醇合成路线 （共 4 条）
反应条件
72 h; Ambient temperature;
参考文献
Conde; Corral; Lissavetzky; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 2 p. 151 - 154
反应条件
1: 64 percent / Na, KI, CuO / 36 h / 90 °C
2: 78 percent / 80percent AcOH / 0.5 h / 60 - 70 °C
3: 1.) TsCl; 2.) 20percent aq. NaOH / 1.) pyridine, 24 h; 2.) DMSO, 15 min
4: 64 percent / 72 h / Ambient temperature
View Scheme
参考文献
Conde; Corral; Lissavetzky; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 2 p. 151 - 154
反应条件
1: 1.) TsCl; 2.) 20percent aq. NaOH / 1.) pyridine, 24 h; 2.) DMSO, 15 min
2: 64 percent / 72 h / Ambient temperature
View Scheme
参考文献
Conde; Corral; Lissavetzky; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 2 p. 151 - 154
反应条件
1: 78 percent / 80percent AcOH / 0.5 h / 60 - 70 °C
2: 1.) TsCl; 2.) 20percent aq. NaOH / 1.) pyridine, 24 h; 2.) DMSO, 15 min
3: 64 percent / 72 h / Ambient temperature
View Scheme
参考文献
Conde; Corral; Lissavetzky; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 2 p. 151 - 154
