2,4-二氯-7-氟-6-甲氧基-喹唑啉合成路线 （共 2 条）
反应条件
N,N-dimethyl-aniline; trichlorophosphate
16 h; Heating;
参考文献
Feng, Jun; Zhang, Zhiyuan; Wallace, Michael B.; Stafford, Jeffrey A.; Kaldor, Stephen W.; Kassel, Daniel B.; Navre, Marc; Shi, Lihong; Skene, Robert J.; Asakawa, Tomoko; Takeuchi, Koji; Xu, Rongda; Webb, David R.; Gwaltney II, Stephen L.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 10 p. 2297 - 2300
反应条件
1: 1.5 h / 200 °C
2: POCl3; N,N-dimethylaniline / 16 h / Heating
View Scheme
参考文献
Feng, Jun; Zhang, Zhiyuan; Wallace, Michael B.; Stafford, Jeffrey A.; Kaldor, Stephen W.; Kassel, Daniel B.; Navre, Marc; Shi, Lihong; Skene, Robert J.; Asakawa, Tomoko; Takeuchi, Koji; Xu, Rongda; Webb, David R.; Gwaltney II, Stephen L.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 10 p. 2297 - 2300
