hydrogen; palladium on activated charcoal in tetrahydrofuran; methanol
18 h; Ambient temperature;
参考文献
Unangst, Paul C.; Capiris, Thomas; Connor, David T.; Heffner, Thomas G.; MacKenzie, Robert G.; Miller, Steven R.; Pugsley, Thomas A.; Wise, Lawrence D.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 17 p. 2688 - 2693
1: 60 percent / H2SO4 / H2O / 48 h / Ambient temperature
2: H2 / 20percent Pd/C / methanol; tetrahydrofuran / 18 h / Ambient temperature
View Scheme
参考文献
Unangst, Paul C.; Capiris, Thomas; Connor, David T.; Heffner, Thomas G.; MacKenzie, Robert G.; Miller, Steven R.; Pugsley, Thomas A.; Wise, Lawrence D.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 17 p. 2688 - 2693
1: 60 percent / H2SO4 / H2O / 48 h / Ambient temperature
2: H2 / 20percent Pd/C / methanol; tetrahydrofuran / 18 h / Ambient temperature
View Scheme
参考文献
Unangst, Paul C.; Capiris, Thomas; Connor, David T.; Heffner, Thomas G.; MacKenzie, Robert G.; Miller, Steven R.; Pugsley, Thomas A.; Wise, Lawrence D.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 17 p. 2688 - 2693