3-(3,4-二氢异喹啉-2(1H)-基)-1-丙醇合成路线 （共 9 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
T=0 - 20°C;
参考文献
Mathis, Cheryl L.; Gist, Brandi M.; Frederickson, Conerd K.; Midkiff, Katie M.; Marvin, Christopher C.
Tetrahedron Letters, 2013 , vol. 54, # 16 p. 2101 - 2104
反应条件
potassium carbonate in acetonitrile
T=60°C; 18 h;
参考文献
Proximagen Limited; Savory, Edward Daniel; Stewart, Allson; Cartey, Allison; Brown, Giles; Simpson, Iain; Oliver, Kathryn; Patient, Lee; Higginbottom, Michael; Cole, Andrew Graham
Patent: US2013/289020 A1, 2013 ;
Location in patent: Paragraph 0357 ;
参考文献
Okimoto, Mitsuhiro; Yoshida, Takashi; Hoshi, Masayuki; Hattori, Kazuyuki; Komata, Masashi; Numata, Kaori; Tomozawa, Kenta
Australian Journal of Chemistry, 2007 , vol. 60, # 4 p. 236 - 242
反应条件
1: acetic acid / 96 h / 80 °C
2: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C
View Scheme
参考文献
Mathis, Cheryl L.; Gist, Brandi M.; Frederickson, Conerd K.; Midkiff, Katie M.; Marvin, Christopher C.
Tetrahedron Letters, 2013 , vol. 54, # 16 p. 2101 - 2104
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Ferles, Miloslav; Kafka, Stanislav
Collection of Czechoslovak Chemical Communications, 1983 , vol. 48, # 4 p. 1068 - 1073
反应条件
1: 2.) NaBH4 / 1.) ethanol, reflux, 80 h, 2.) 90 deg C, 2 h.
2: 30 percent
View Scheme
参考文献
Ferles, Miloslav; Silhankova, Alexandra; Kafka, Stanislav; Taufmann, Petr; Motacek, Tomas
Collection of Czechoslovak Chemical Communications, 1983 , vol. 48, # l p. 1759 - 1764
参考文献
Ferles, Miloslav; Silhankova, Alexandra; Kafka, Stanislav; Taufmann, Petr; Motacek, Tomas
Collection of Czechoslovak Chemical Communications, 1983 , vol. 48, # l p. 1759 - 1764
反应条件
benzene
nachfolgend Verseifung mit waessrig-alkoholischer Kalilauge;
参考文献
v. Braun; Braunsdorf; Raeth
Chemische Berichte, 1922 , vol. 55, p. 1679
反应条件
Yield given. Multistep reaction;
参考文献
Ferles, Miloslav; Kafka, Stanislav
Collection of Czechoslovak Chemical Communications, 1983 , vol. 48, # 4 p. 1068 - 1073
