3-甲氧基苯甲酰基甲酸乙酯合成路线 （共 7 条）
反应条件
boric acid; [Rh(OH)(cycloocta-1,5-diene)]2 in 1,4-dioxane T=60°C; 3 h;
参考文献
Shimizu, Hiroshi; Murakami, Masahiro
Chemical Communications, 2007 , # 27 p. 2855 - 2857
反应条件
in tetrahydrofuran; diethyl ether T=-78 - 10°C;
参考文献
US2008/96891 A1, ;
Page/Page column 15 ;
反应条件
1: ethanol With selenium(IV) oxide 0.166667 h; Heating / reflux; 2: 1-bromo-2-(3-methoxyphenyl)-2-oxoethane Heating / reflux;
参考文献
ALMIRALL PRODESFARMA S.A.
Patent: WO2006/122788 A1, 2006 ;
Location in patent: Page/Page column 67-68 ;
WO 2006/122788 A1
反应条件
lithium diisopropyl amide in tetrahydrofuran T=-78 - 20°C;
参考文献
Thasana, Nopporn; Prachyawarakorn, Vilailak; Tontoolarug, Sopchok; Ruchirawat, Somsak
Tetrahedron Letters, 2003 , vol. 44, # 5 p. 1019 - 1021
反应条件
1: 3-methoxybromobenzene With iodine; magnesium in tetrahydrofuran Inert atmosphere; 2: oxalic acid diethyl ester in tetrahydrofuran T=-78 - 20°C; 14 h; Inert atmosphere;
参考文献
Organic Letters, , vol. 13, # 24 p. 6520 - 6523
反应条件
potassium fluoride; tetrabutyl ammonium fluoride; methyl iodide in tetrahydrofuran T=20°C; 16 h; Inert atmosphere; chemoselective reaction;
参考文献
Metz, Alison E.; Kozlowski, Marisa C.
Journal of Organic Chemistry, 2013 , vol. 78, # 2 p. 717 - 722
反应条件
1: 76 percent / BTAC / CH2Cl2; H2O / 20 °C 2: 67 percent / LDA / tetrahydrofuran / -78 - 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 44, # 5 p. 1019 - 1021
