1,3-二乙酰氧-2-(乙酰氧基甲氧基)丙烷合成路线 （共 13 条）
反应条件
boron trifluoride-diethyl ether complex; sodium hydrogencarbonate in H2; acetic anhydride
反应条件
1: dimethylformamide / Heating 2: BF3*Et2O / 0 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 31, # 1 p. 144 - 149
反应条件
boron trifluoride diethyl etherate T=0°C;
参考文献
Journal of Medicinal Chemistry, , vol. 31, # 1 p. 144 - 149
反应条件
in N,N-dimethyl-formamide 2 h; Heating;
参考文献
Synthesis, , # 4 p. 625 - 628
反应条件
acetic acid; zinc(II) chloride 4.5 h; Ambient temperature;
参考文献
Journal of Medicinal Chemistry, , vol. 28, # 7 p. 926 - 933
反应条件
in N,N-dimethyl-formamide 1.)140 deg C, 6 h 2.)20 deg C, 18 h;
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 24, p. 163 - 167
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 24, # 2 p. 198 - 202
反应条件
1: With 4-hydroxybenzenesulfonic acid in DMF (N,N-dimethyl-formamide) T=95 - 100°C; 42 h; 2: in methanol T=20°C; 3: T=0 - 5°C; 0.5 h;
参考文献
RANBAXY LABORATORIES LIMITED
Patent: WO2004/48380 A1, 2004 ;
Location in patent: Page 7 ;
反应条件
phosphoric acid in chloroform; N,N-dimethyl-formamide
参考文献
University of Georgia Research Foundation, Inc.
Patent: US5583225 A1, 1996 ;
反应条件
toluene-4-sulfonic acid in chlorobenzene 2 h; Heating;
参考文献
Synthesis, , # 4 p. 625 - 628
反应条件
1: 38 percent / p-TsOH*H2O / chlorobenzene / 2 h / Heating 2: 50 percent / 0.17 h / 230 °C View Scheme
参考文献
Boryski, Jerzy; Golankiewicz, Bozenna
Synthesis, 1999 , # 4 p. 625 - 628
