噻吩并[2,3-b]吡啶-6-甲腈合成路线 （共 12 条）
参考文献
Walker, Daniel Patrick; Piotrowski, David W.; Jacobsen, Eric Jon; Acker, Brad A.; Wishka, Donn G.; Reitz, Steven Charles; Groppi JR., Vincent E.
Patent: US2003/153595 A1, 2003 ;
参考文献
Wishka, Donn G.; Reitz, Steven Charles; Piotrowski, David W.; Groppi JR., Vincent E.
Patent: US2003/45540 A1, 2003 ;
反应条件
benzoyl chloride in dichloromethane; water
T=25°C; 16 h;
参考文献
Klemm, L. H.; Muchiri, Daniel R.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 213 - 217
反应条件
in dichloromethane; water
T=25°C; 16 h;
参考文献
Klemm, L. H.; Muchiri, Daniel R.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 213 - 217
反应条件
1: H2O2, HOAc / 55 °C
2: 46 percent / benzoyl chloride / CH2Cl2; H2O / 16 h / 25 °C
View Scheme
参考文献
Klemm, L. H.; Muchiri, Daniel R.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 213 - 217
反应条件
in methanol
12 h; Ambient temperature;
参考文献
Klemm, L. H.; Muchiri, Daniel R.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1717 - 1719
反应条件
in ethanol
12 h; Ambient temperature;
参考文献
Klemm, L. H.; Muchiri, Daniel R.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1717 - 1719
反应条件
in butan-1-ol
12 h; Ambient temperature;
参考文献
Klemm, L. H.; Muchiri, Daniel R.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1717 - 1719
反应条件
1: 87 percent / methanol / 12 h / Ambient temperature
2: 36 percent / triethylamine / CHCl3 / 12 h / Heating
3: 80 percent / sodium ethoxide / 24 h / Heating
View Scheme
参考文献
Klemm, L. H.; Muchiri, Daniel R.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1717 - 1719
反应条件
1: 87 percent / methanol / 12 h / Ambient temperature
2: 84 percent / ammonium chloride / aq. ethanol / 24 h / Heating
View Scheme
参考文献
Klemm, L. H.; Muchiri, Daniel R.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1717 - 1719
