4-(4-羟基苯基)-1-丁醇合成路线 （共 13 条）
反应条件
1: 82.3 g / K2CO3, KI / butan-2-one / 24 h / Heating
2: aq. KOH / aq. ethanol / 3 h / Heating
View Scheme
参考文献
Martin, Lawrence L.; Setescak, Linda L.; Spaulding, Theodore C.; Helsley, Grover C.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 372 - 376
反应条件
1: 82.3 g / K2CO3, KI / butan-2-one / 24 h / Heating
2: aq. KOH / aq. ethanol / 3 h / Heating
3: 84 percent / CH2Cl2 / 4 h / Heating
4: 90 percent / 0.7 M HCl / acetone / 20 h / Heating
View Scheme
参考文献
Martin, Lawrence L.; Setescak, Linda L.; Spaulding, Theodore C.; Helsley, Grover C.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 372 - 376
反应条件
bromine; triphenylphosphine in dichloromethane
参考文献
Eli Lilly and Company
Patent: US5952360 A1, 1999 ;
